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IKarisoside A is a natural compound isolated from Epimedium koreanum (Berberidaceae) with anti-inflammatory properties. IKarisoside A possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. Ikarisoside A reduced the release of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta). Furthermore, Ikarisoside A inhibited the activity of p38 kinase and nuclear factor-kappaB.
Molecular Weight | 500.49 |
Formula | C26H28O10 |
CAS Number | 55395-07-8 |
Solubility (25°C) | Soluble in DMSO |
Storage | 2-8°C, protect from light, sealed |
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