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IKarisoside A

Cat. No. M10351

All AbMole products are for research use only, cannot be used for human consumption.

IKarisoside A Structure
Synonym:

Baohuoside II

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5mg USD 380  USD380 In stock
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Quality Control & Documentation
Biological Activity

IKarisoside A is a natural compound isolated from Epimedium koreanum (Berberidaceae) with anti-inflammatory properties. IKarisoside A possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. Ikarisoside A reduced the release of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta). Furthermore, Ikarisoside A inhibited the activity of p38 kinase and nuclear factor-kappaB.

Chemical Information
Molecular Weight 500.49
Formula C26H28O10
CAS Number 55395-07-8
Solubility (25°C) Soluble in DMSO
Storage 2-8°C, protect from light, sealed
References

[1] Hwa Jung Choi, et al. Eur J Pharmacol. Inhibition of osteoclastogenic differentiation by Ikarisoside A in RAW 264.7 cells via JNK and NF-kappaB signaling pathways

[2] Hwa Jung Choi, et al. Eur J Pharmacol. Ikarisoside A inhibits inducible nitric oxide synthase in lipopolysaccharide-stimulated RAW 264.7 cells via p38 kinase and nuclear factor-kappaB signaling pathways

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Keywords: IKarisoside A, Baohuoside II supplier, Others, inhibitors, activators

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