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IDE 1 is a induces definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 125 nM). Thought to activate the TGF-β signaling pathway; induces Smad2 phosphorylation and increases levels of Nodal expression.This compound is mixture of E/Z isomers.
| Molecular Weight | 306.31 |
| Formula | C15H18N2O5 |
| CAS Number | 1160927-48-9 |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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