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Icosabutate

Cat. No. M40991

All AbMole products are for research use only, cannot be used for human consumption.

Icosabutate Structure

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Quality Control & Documentation
Biological Activity

Icosabutate is an orally active omega-3 polyunsaturated fatty acid and an eicosapentaenoic acid derivative (EPA derivative) that has been used in studies related to non-alcoholic steatohepatitis (NASH).

Chemical Information
Molecular Weight 374.56
Formula C24H38O3
CAS Number 1253909-57-7
Form Liquid
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] David A Fraser et al. Expert Opin Investig Drugs. Icosabutate: targeting metabolic and inflammatory pathways for the treatment of NASH

[2] David A Fraser et al. J Hepatol. A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH

[3] Anita M van den Hoek et al. Hepatol Commun. Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice

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Keywords: Icosabutate supplier, inhibitors, activators

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