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Iclepertin

Cat. No. M21103

All AbMole products are for research use only, cannot be used for human consumption.

Iclepertin Structure
Synonym:

BI-425809

Size Price Availability Quantity
5mg USD 670  USD670 In stock
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Quality Control & Documentation
Biological Activity

Iclepertin (BI 425809) is an oral glycine transporter-1 (GlyT1) inhibitor being developed for the study of cognitive impairment associated with schizophrenia (CIAS).

Chemical Information
Molecular Weight 512.42
Formula C20H18F6N2O5S
CAS Number 1421936-85-7
Solubility (25°C) DMSO : 11.36 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Christian Schultheis, et al. Transl Psychiatry. Quantitative electroencephalography parameters as neurophysiological biomarkers of schizophrenia-related deficits: A Phase II substudy of patients treated with iclepertin (BI 425809)

[2] Holger Rosenbrock, et al. J Pharmacol Exp Ther. Effects of the Glycine Transporter-1 Inhibitor Iclepertin (BI 425809) on Sensory Processing, Neural Network Function, and Cognition in Animal Models Related to Schizophrenia

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Keywords: Iclepertin, BI-425809 supplier, inhibitors, activators

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