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HOIPIN-1

Cat. No. M20818

All AbMole products are for research use only, cannot be used for human consumption.

HOIPIN-1 Structure
Synonym:

JTP-0819958, HOIP inhibitor-1

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Quality Control & Documentation
Biological Activity

HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a linear ubiquitin chain assembly complex (LUBAC) inhibitor with an IC50 of 2.8 μM for inhibiting the in vitro linear ubiquitination activity of the petit-LUBAC.

Chemical Information
Molecular Weight 304.27
Formula C17H13NaO4
Solubility (25°C) DMSO 5 mg/mL
Water 61 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Daisuke Oikawa, et al. Commun Biol. Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses

[2] Ken Katsuya, et al. Biochem Biophys Res Commun. Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling

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Keywords: HOIPIN-1, JTP-0819958, HOIP inhibitor-1 supplier, inhibitors, activators

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