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HM03

Cat. No. M10496

All AbMole products are for research use only, cannot be used for human consumption.

HM03 Structure
Synonym:

HM-03; NSC130813

Size Price Availability Quantity
10mg USD 78  USD78 In stock
25mg USD 150  USD150 In stock
50mg USD 230  USD230 In stock
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Quality Control & Documentation
Biological Activity

HM03 is a potent and selective HSPA5 (also known as Bip, Grp78) inhibitor with anticancer activity. HM03 forms more binding interactions with HSPA5 and HSPA9 than with the other HSP70 proteins.

Chemical Information
Molecular Weight 462.97
Formula C26H27ClN4O2
CAS Number 500565-15-1
Solubility (25°C) DMSO 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Meilan Huang, et al. Bioorg Med Chem Lett. Structure-based design of HSPA5 inhibitors: from peptide to small molecule inhibitors

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Hsp70-derived octapeptide

Hsp70-derived octapeptide is a conserved octapeptide of the C-terminal end of Hsp70, which physically interacts with tetratricopeptide repeat (TPR) motifs.

  Catalog
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Keywords: HM03, HM-03; NSC130813 supplier, HSP, inhibitors, activators

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