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Histamine is an endogenous ligand for histamine receptors, which can cause allergic reactions by interacting with H1 receptors, promote acid secretion by interacting with H2 receptors, as well as inhibit histamine release and modulate immune responses by interacting with H3 receptors and H4 receptors. It can be used in studies related to allergy, hyperacidity, sleep disorders, asthma and many other diseases.
| Molecular Weight | 111.15 |
| Formula | C5H9N3 |
| CAS Number | 51-45-6 |
| Solubility (25°C) | 34 mg/mL in water |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Histamine Receptor Products |
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| Dimethindene
Dimethindene is a potent, selective histamine H1 antagonist. |
| ABT-288
ABT-288 is a competitive, potent and selective histamine H3 receptor (H3R) antagonist. |
| A-349821
A-349821 is a histamine H3 receptor antagonist characterized as a radioligand ([3H]-A-349821) for in vivo receptor occupancy assessment. |
| Betazole
Betazole (Ametazole), a pyrazole analogue of histamine, is an orally active histamine H2 receptor agonist. |
| Tiotidine
Tiotidine (ICI 125211) is a potent and selective antagonist of histamine H2-receptor (pA2=7.3-7.8 for guinea-pig right atrium). |
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