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Heme Oxygenase-1-IN-1

Cat. No. M14112

All AbMole products are for research use only, cannot be used for human consumption.

Heme Oxygenase-1-IN-1 Structure

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Quality Control & Documentation
Biological Activity

Heme Oxygenase-1-IN-1 (Compound 2) is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 250 nM.

Chemical Information
Molecular Weight 279.18
CAS Number 1093058-52-6
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Toru Shimizu, et al. Heme: emergent roles of heme in signal transduction, functional regulation and as catalytic centres

[2] Lisa Marie Schmitz, et al. Recent advances in heme biocatalysis engineering

[3] David A Gell. Structure and function of haemoglobins

[4] Tohru Fujiwara, et al. Biology of Heme in Mammalian Erythroid Cells and Related Disorders

[5] Andrew G Smith, et al. The regulatory role of heme in neurons

Related Heme oxygenase Products
Heme Oxygenase-1-IN-1 hydrochloride

Heme Oxygenase-1-IN-1 hydrochloride (Compound 2) is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 250 nM.

Coniferaldehyde

Coniferaldehyde (Ferulaldehyde) is a potent inducer of heme oxygenase-1 (HO-1) with anti-inflammatory effects. In RAW264.7 macrophages, Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/βII/Nrf-2/HO-1-dependent pathway.

Zinc Protoporphyrin

Zinc Protoporphyrin is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor.

Hemin chloride

Hemin is an iron-containing porphyrinis potentially for the treatment of gastroparesis.

Tin protoporphyrin IX dichloride

Tin protoporphyrin IX dichloride is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin-protoporphyrin IX (SnPPIX) sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model.

  Catalog
Abmole Inhibitor Catalog




Keywords: Heme Oxygenase-1-IN-1 supplier, Heme oxygenase, inhibitors, activators

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