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Zinc Protoporphyrin

Cat. No. M10187

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Zinc Protoporphyrin Structure
Synonym:

ZnPPIX; zinc protoporphyrin IX; Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9

Size Price Availability Quantity
1mg USD 40  USD40 In stock
5mg USD 170  USD170 In stock
10mg USD 280  USD280 In stock
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Quality Control & Documentation
Biological Activity

Zinc Protoporphyrin is an orally active and competitive heme oxygenase-1 (HO-1) inhibitor.

Product Citations
Chemical Information
Molecular Weight 626.02
Formula C34H32N4O4Zn
CAS Number 15442-64-5
Solubility (25°C) DMSO 50 mg/mL
Storage -20°C, dry, sealed
References

[1] Dongdong Li, et al. Life Sci. Heme oxygenase-1 alleviated non-alcoholic fatty liver disease via suppressing ROS-dependent endoplasmic reticulum stress

[2] Xinnong Liu, et al. Oxid Med Cell Longev. Isoliquiritigenin Ameliorates Acute Pancreatitis in Mice via Inhibition of Oxidative Stress and Modulation of the Nrf2/HO-1 Pathway

[3] Min-Young Kwon, et al. Oncotarget. Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death

[4] Dominika Nowis, et al. BMC Cancer. Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice

[5] Xing Rong, et al. Zhonghua Er Ke Za Zhi. Effects of hemoglobin oxygenase-1 inhibitor zinc protoporphyrin IX on acute viral myocarditis in mice

[6] Kaeko Hirai, et al. Int J Cancer. Inhibition of heme oxygenase-1 by zinc protoporphyrin IX reduces tumor growth of LL/2 lung cancer in C57BL mice

Related Heme oxygenase Products
Heme Oxygenase-1-IN-1 hydrochloride

Heme Oxygenase-1-IN-1 hydrochloride (Compound 2) is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 250 nM.

Heme Oxygenase-1-IN-1

Heme Oxygenase-1-IN-1 (Compound 2) is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 250 nM.

Coniferaldehyde

Coniferaldehyde (Ferulaldehyde) is a potent inducer of heme oxygenase-1 (HO-1) with anti-inflammatory effects. In RAW264.7 macrophages, Coniferaldehyde inhibits LPS-induced apoptosis through the PKCα/βII/Nrf-2/HO-1-dependent pathway.

Hemin chloride

Hemin is an iron-containing porphyrinis potentially for the treatment of gastroparesis.

Tin protoporphyrin IX dichloride

Tin protoporphyrin IX dichloride is a potent Heme oxygenase-1 (HO-1) inhibitor. Tin-protoporphyrin IX (SnPPIX) sensitizes pancreatic ductal adenocarcinoma (PDAC) tumors to chemotherapy in mice model.

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Keywords: Zinc Protoporphyrin, ZnPPIX; zinc protoporphyrin IX; Zn(II)-protoporphyrin IX; ZnPP; Zinc Protoporphyrin-9 supplier, Heme oxygenase, inhibitors, activators

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