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Harmane

Cat. No. M44871

All AbMole products are for research use only, cannot be used for human consumption.

Harmane Structure
Synonym:

Harman

Size Price Availability Quantity
50mg USD 60  USD60 In stock
100mg USD 100  USD100 In stock
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Quality Control & Documentation
Biological Activity

Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC50s=0.5 and 5 μM for human MAO A/B, respectively).

Chemical Information
Molecular Weight 182.22
Formula C12H10N2
CAS Number 486-84-0
Form Solid
Solubility (25°C) DMSO 90 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bao Tan Nguyen, et al. J Pharm Biomed Anal. Lipid class-dependent alterations of Caenorhabditis elegans under harmane exposure

[2] Zheng Ding, et al. Front Mol Neurosci. Harmane Potentiates Nicotine Reinforcement Through MAO-A Inhibition at the Dose Related to Cigarette Smoking

[3] Yanwen Li, et al. RSC Adv. Harmane ameliorates obesity though inhibiting lipid accumulation and inducing adipocyte browning

[4] Haroon Khan, et al. Curr Drug Metab. Pharmacological and Toxicological Profile of Harmane-β-Carboline Alkaloid: Friend or Foe

[5] Haya Abu Ghazaleh, et al. Neurosci Lett. Harmane: an atypical neurotransmitter?

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Keywords: Harmane, Harman supplier, Imidazoline Receptor, inhibitors, activators

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