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Halopemide is a dopamine receptor antagonist and a phospholipase D2 inhibitor. Halopemide may be used as a screen to identify inhibitors of human PLD2 using an in vitro biochemical assay. It is also inhibitory at benzodiazepine binding sites.
| Molecular Weight | 416.88 |
| Formula | C21H22ClFN4O2 |
| CAS Number | 59831-65-1 |
| Solubility (25°C) | DMSO: ≥10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Lauren Monovich, et al. Optimization of halopemide for phospholipase D2 inhibition
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