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H-gamma-Glu-Phe-OH

Cat. No. M10239
H-gamma-Glu-Phe-OH Structure
Synonym:

γ-Glu-Phe; γ-Glutamylphenylalanine

Size Price Availability
10mg USD 108  USD120 4-7 Days
25mg USD 180  USD200 4-7 Days
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Quality Control
  • Current batch:
  • Purity >99.5%
  • COA
  • MSDS
Biological Activity

γ-Glu-Phe (γ-Glutamylphenylalanine) is a γ-3 glutamyl dipeptide synthesized by Bacillus amyloliquefaciens (GBA) and Aspergillus oryzae (GAO). Proteolysis is an important factor for generation of γ-glutamyl dipeptides. Sensory evaluation of bread reveals that sourdough bread with higher concentrations of γ-glutamyl dipeptides ranks higher with respect to the taste intensity when compared to regular bread and type I sourdough bread.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 294.3
Formula C14H18N2O5
CAS Number 7432-24-8
Purity >99.5%
Solubility Water 45 mg/mL
Storage -20°C, sealed
References

Synthesis and Sensory Characteristics of Kokumi γ-[Glu] n-Phe in the Presence of Glutamine and Phenylalanine: Glutaminase from Bacillus amyloliquefaciens or Aspergillus oryzae as the Catalyst
Juan Yang, et al. J Agric Food Chem. 2017 Oct 4;65(39):8696-8703. PMID: 28899090.

Serum metabolomic profiling of prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trial
Jiaqi Huang, et al. Br J Cancer. 2016 Oct 25;115(9):1087-1095. PMID: 27673363.

Improvement of the bitter taste of amino acids through the transpeptidation reaction of bacterial gamma-glutamyltranspeptidase
Hideyuki Suzuki, et al. J Agric Food Chem. 2002 Jan 16;50(2):313-8. PMID: 11782200.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: H-gamma-Glu-Phe-OH, γ-Glu-Phe; γ-Glutamylphenylalanine supplier, Endogenous Metabolite, inhibitors

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