All AbMole products are for research use only, cannot be used for human consumption.
GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ.
Transl Neurosci. 2023 Mar 6;14(1):20220277.
Omega-3 polyunsaturated fatty acids alleviate early brain injury after traumatic brain injury by inhibiting neuroinflammation and necroptosis
GW9662 purchased from AbMole
Acta Pharmacol Sin. 2020 Mar;41(3):373-382.
Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ
GW9662 purchased from AbMole
J Cell Mol Med. 2020 Jun;24(12):6833-6845.
Seizure-induced impairment in neuronal ketogenesis: Role of zinc-α2-glycoprotein in mitochondria
GW9662 purchased from AbMole
Life Sci. 2019 Dec 1;238:116979.
Effects of progesterone on glucose uptake in neurons of Alzheimer's disease animals and cell models.
GW9662 purchased from AbMole
Molecular Weight | 276.68 |
Formula | C13H9ClN2O3 |
CAS Number | 22978-25-2 |
Solubility (25°C) | DMSO ≥ 40 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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