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GTS-21

Cat. No. M8293

All AbMole products are for research use only, cannot be used for human consumption.

GTS-21 Structure
Synonym:

DMXB-A; DMBX-anabaseine

Size Price Availability Quantity
1mg USD 40  USD40 In stock
5mg USD 60  USD60 In stock
10mg USD 94  USD94 In stock
50mg USD 350  USD350 In stock
100mg USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

GTS-21 is a selective agonist at α-7 nicotinic receptors with anti-inflammatory and cognition enhancing activities. GTS-21 has also been investigated for the treatment of schizophrenia.

Chemical Information
Molecular Weight 381.3
Formula C19H20N2O2 · 2HCl
CAS Number 156223-05-1
Solubility (25°C) Water: ≥5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Malgorzata A Kolodziej, et al. Antiproliferative effect of GTS-21 in glioblastoma cells

[2] Yinhui Zhou, et al. Nonopioid GTS-21 Mitigates Burn Injury Pain in Rats by Decreasing Spinal Cord Inflammatory Responses

[3] Haisong Wang, et al. GTS-21 Promotes α7 nAChR to Alleviate Intestinal Ischemia-Reperfusion-Induced Apoptosis and Inflammation of Enterocytes

[4] Xiao-Jing Wu, et al. GTS-21 ameliorates polymicrobial sepsis-induced hepatic injury by modulating autophagy through α7nAchRs in mice

[5] Brijesh K Garg, et al. GTS-21 has cell-specific anti-inflammatory effects independent of α7 nicotinic acetylcholine receptors

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Keywords: GTS-21, DMXB-A; DMBX-anabaseine supplier, inhibitors, activators

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