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GSK467

Cat. No. M13832

All AbMole products are for research use only, cannot be used for human consumption.

GSK467 Structure
Size Price Availability Quantity
1mg USD 70  USD70 In stock
5mg USD 180  USD180 In stock
10mg USD 280  USD280 In stock
25mg USD 440  USD440 In stock
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Quality Control & Documentation
Biological Activity

GSK467 is a cell penetrant and selective KDM5B (JARID1B or PLU1) inhibitor with a Ki of 10 nM, shows 180-fold selectivity for KDM4C and no measurable inhibitory effects toward KDM6 or other Jumonji family members.

Chemical Information
Molecular Weight 319.32
CAS Number 1628332-52-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sarder Arifuzzaman, et al. Pharmacol Res. Research update and opportunity of non-hormonal male contraception: Histone demethylase KDM5B-based targeting

[2] Catrine Johansson, et al. Nat Chem Biol. Structural analysis of human KDM5B guides histone demethylase inhibitor development

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Keywords: GSK467 supplier, Histone demethylase, inhibitors, activators

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