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GPV574

Cat. No. M8237

All AbMole products are for research use only, cannot be used for human consumption.

GPV574 Structure

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Quality Control & Documentation
Biological Activity

GPV574 is a derivative of the Class 1C antiarrhythmic compound propafenone. GPV574 inhibits the delayed rectifier K+ channel HERG with similar affinity and time constant as propafenone (IC50 = 5 mM), but unlike the parent compound, does not remain permanently trapped in the channel pore. After wash-out of GPV574, channel activity is recovered within 60 seconds.

Chemical Information
Molecular Weight 382.5
Formula C23H30N2O3
CAS Number 635703-12-7
Solubility (25°C) DMSO: ≥10 mg/mL (warmed to 60°C)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
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  Catalog
Abmole Inhibitor Catalog




Keywords: GPV574 supplier, inhibitors, activators

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