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Golodirsen

Cat. No. M40950

All AbMole products are for research use only, cannot be used for human consumption.

Golodirsen Structure
Synonym:

SRP-4053

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Quality Control & Documentation
Biological Activity

Golodirsen is a phosphodiesteric morpholino oligomer (PMO) that specifically targets exon 53 of the pre-protein mRNA of myotonic dystrophy protein culture proteins, and can be used in studies related to Duchenne muscular dystrophy (DMD).

Chemical Information
Molecular Weight 8647.00
CAS Number 1422959-91-8
Form Solid
Solubility (25°C) Water 100 mg/mL
Storage -20°C, dry
References

[1] Laurent Servais et al. Nucleic Acid Ther. Long-Term Safety and Efficacy Data of Golodirsen in Ambulatory Patients with Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping: A First-in-human, Multicenter, Two-Part, Open-Label, Phase 1/2 Trial

[2] S Anwar et al. Drugs Today (Barc). Golodirsen for Duchenne muscular dystrophy

[3] Diane E Frank et al. Neurology. Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy

[4] Young-A Heo. Drugs. Golodirsen: First Approval

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Keywords: Golodirsen, SRP-4053 supplier, inhibitors, activators

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