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Gly-Phe β-naphthylamide (Gly-Phe beta-naphthylamide) is a substrate of cathepsin C that accumulates within the lysosome. Gly-Phe-β-naphthylamide can inhibit the cathepsin-dependent activation of caspase-8.
| Molecular Weight | 347.41 |
| Formula | C21H21N3O2 |
| CAS Number | 21438-66-4 |
| Solubility (25°C) | DMSO 69 mg/mL Water 2 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Yu Yuan, et al. J Cell Sci. The lysosomotrope GPN mobilises Ca2+ from acidic organelles
[5] M Jadot, et al. Biochem J. Intralysosomal hydrolysis of glycyl-L-phenylalanine 2-naphthylamide
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