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Gly-β-MCA

Cat. No. M10251

All AbMole products are for research use only, cannot be used for human consumption.

Gly-β-MCA Structure
Synonym:

Glycine-β-muricholic Acid

Size Price Availability
1mg USD 260  USD260 4-7 Days
5mg USD 560  USD560 4-7 Days
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Quality Control & Documentation
Biological Activity

Gly-β-MCA is a potent, stable, intestine-selective and oral bioactive farnesoid X receptor (FXR) inhibitor. Gly-β-MCA (Gly-MCA, 10 and 50 mg/kg; p.o.) prevents and treats diet-induced and genetic obesity, along with insulin resistance and hepatic steatosis without systemic, hepatic or intestinal toxicities in mice.

Chemical Information
Molecular Weight 465.62
Formula C26H43NO6
CAS Number 66225-78-3
Solubility (25°C) DMSO 100 mg/mL
Storage -20°C, sealed
References

[1] Changtao Jiang, et al. Nat Commun. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction

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  Catalog
Abmole Inhibitor Catalog




Keywords: Gly-β-MCA, Glycine-β-muricholic Acid supplier, Farnesoid X Receptor, inhibitors, activators

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