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Gibberellin A7

Cat. No. M39792
Gibberellin A7 Structure
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Biological Activity

Gibberellin A7 (GA7) is a plant hormone. Gibberellin A7 is the metabolite of Gibberella fujikuroi. Gibberellin A7 promotes the plant growth and elongation of cells.

Chemical Information
Molecular Weight 330.37
Formula C19H22O5
CAS Number 510-75-8
Form Solid
Storage Powder -20°C
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] T Iizuka et al. Front Allergy. Gibberellin-regulated proteins: Emergent allergens

[2] Bruno Dias Nani et al. Pharmaceutics. A Study on the Anti-NF-κB, Anti- Candida, and Antioxidant Activities of Two Natural Plant Hormones: Gibberellin A4 and A7

[3] M Katsumi et al. Plant Cell Physiol. Physiological effects of cotyledons on gibberellin-induced cucumber hypocotyl elongation

[4] T Hashimoto. Plant Physiol. Gibberellin Structure-Dependent Interaction between Gibberellins and Deoxygibberellin C in the Growth of Dwarf Maize Seedlings

[5] H L Greenwood. J Protozool. The effects of actinomycin D, gibberellin A7, and cyclic AMP on mating of Chlamydomonas reinhardtii

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