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Gevokizumab is a potent anti-IL-1β antibody, negatively modulates IL-1β signaling through an allosteric mechanism. Gevokizumab selectively decreases the binding affinity of IL-1β for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor type II).
| CAS Number | 1129435-60-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[3] Wen-Ming Wang, et al. Expert Opin Drug Saf. Biologics in the treatment of pustular psoriasis
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