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Gatifloxacin sesquihydrate

Cat. No. M28883

All AbMole products are for research use only, cannot be used for human consumption.

Gatifloxacin sesquihydrate Structure
Synonym:

AM-1155 sesquihydrate; BMS-206584 sesquihydrate; PD135432 sesquihydrate

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Quality Control & Documentation
Biological Activity

Gatifloxacin sesquihydrate (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin sesquihydrate inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin sesquihydrate can be used to treat bacterial conjunctivitis in vivo.

Chemical Information
Molecular Weight 402.43
Formula C19H22FN3O4.3/2H2O
CAS Number 180200-66-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Reem N El Gammal, et al. J Chromatogr Sci. Simultaneous Determination of Gatifloxacin and Prednisolone in their Bulk Powder, Synthetic Mixture and Their Combined Ophthalmic Preparation Using Micellar Liquid Chromatography

[2] Gaurav Khurana, et al. Int J Pharm Investig. Ocular insert for sustained delivery of gatifloxacin sesquihydrate: Preparation and evaluations

[3] R M Gilhotra, et al. Pharmazie. Alginate-chitosan film for ocular drug delivery: effect of surface cross-linking on film properties and characterization

[4] Monique Y Wells, et al. Exp Toxicol Pathol. Cerebral vacuolation induced in rats by the administration of LUP-3FDC, an anti-tuberculosis cocktail

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Keywords: Gatifloxacin sesquihydrate, AM-1155 sesquihydrate; BMS-206584 sesquihydrate; PD135432 sesquihydrate supplier, Antibiotic, inhibitors, activators

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