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Cat. No. M24914

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Garetosmab Structure

REGN 2477

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Biological Activity

Garetosmab (REGN 2477) is a fully human IgG4 monoclonal antibody that specifically inhibits activin A. Garetosmab can be used for fibrodysplasia ossificans progressiva (FOP) research.

Chemical Information
CAS Number 2097125-54-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.

[1] Robert J Pignolo, et al. Cells. Retinoid Agonists in the Targeting of Heterotopic Ossification

[2] Hélène Kaplon, et al. MAbs. Antibodies to watch in 2021

[3] Frédéric Vanhoutte, et al. J Clin Pharmacol. Pharmacokinetics and Pharmacodynamics of Garetosmab (Anti-Activin A): Results From a First-in-Human Phase 1 Study

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Keywords: Garetosmab, REGN 2477 supplier, TGF-beta/Smad, inhibitors, activators

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