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G3-C12 is a galectin-3 binding peptide, with Kd of 88 nM, and shows anticancer activity. G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.
Sequence: Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg
| Molecular Weight | 1758.98 |
| Formula | C74H115N23O23S2 |
| CAS Number | 848301-94-0 |
| Solubility (25°C) | Water 100 mg/mL |
| Storage | -20°C, dry, sealed |
[5] Kam Leung. 111In-Tetraazacyclododecane- N, N’, N’’, N’’’-tetraacetic acid-(GSG)-ANTPCGPYTHDCPVKR
| Related Galectin Products |
|---|
| Galectin-3 antagonist 1
Galectin-3 antagonist 1 is a potent and selective Galectin-3 (Gal-3) antagonist with Kd value of 5.3 μM. |
| Galectin-3/galectin-8-IN-2
Galectin-3/galectin-8-IN-2 is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 12.8 μM and 2.06 μM respectively. |
| Galectin-3/galectin-8-IN-1
Galectin-3/galectin-8-IN-1 is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 4.12 μM and 6.04 μM respectively. |
| Belapectin
Belapectin, a galectin 3 inhibitor with a Ki value of 2.8 μM, reduces hepatic fibrosis and portal hypertension in rats, and can be used in studies related to non-alcoholic steatohepatitis (NASH). |
| Selvigaltin
Selvigaltin (GB1211) is an orally available galectin-3 (Gal-3) inhibitor. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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