Free shipping on all orders over $ 500

Fumarate hydratase-IN-1

Cat. No. M22353

All AbMole products are for research use only, cannot be used for human consumption.

Fumarate hydratase-IN-1 Structure
Size Price Availability Quantity
2mg USD 165  USD165 In stock
5mg USD 260  USD260 In stock
10mg USD 360  USD360 In stock
25mg USD 720  USD720 In stock
50mg USD 1120  USD1120 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Fumarate hydratase-IN-1 is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM.

Chemical Information
Molecular Weight 446.54
Formula C27H30N2O4
CAS Number 1644060-37-6
Solubility (25°C) DMSO 45 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Irena Majkutewicz. Eur J Pharmacol. Dimethyl fumarate: A review of preclinical efficacy in models of neurodegenerative diseases

[2] Julia Paik. CNS Drugs. Diroximel Fumarate in Relapsing Forms of Multiple Sclerosis: A Profile of Its Use

[3] Duvyanshu Dubey, et al. Expert Rev Neurother. Dimethyl fumarate in relapsing-remitting multiple sclerosis: rationale, mechanisms of action, pharmacokinetics, efficacy and safety

[4] Celeste B Burness, et al. CNS Drugs. Dimethyl fumarate: a review of its use in patients with relapsing-remitting multiple sclerosis

[5] Take-Aki Mitsudo, et al. Chem Rec. Chemistry of Ru(eta6-1,3,5-cyclooctatriene)(eta2-dimethyl fumarate)2

Related Mitochondrial Related Products
MFI8 

MFI8 is a small molecule inhibitor of mitochondrial.

GW604714X 

GW604714X is a potent inhibitor of mitochondrial respiration supported by pyruvate but not other substrates.

Antimalarial agent 14 

Antimalarial agent 14 is a potent inhibitor of mitochondrial electron transport.

IM176OUT05

IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC50 of 3.2 μM. IM176OUT05 is a high solubility biguanide.

THP104c

THP104c is a mitochondrial fission inhibitor.

  Catalog
Abmole Inhibitor Catalog




Keywords: Fumarate hydratase-IN-1 supplier, Mitochondrial Related, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.