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Fumagillol

Cat. No. M27761

All AbMole products are for research use only, cannot be used for human consumption.

Fumagillol Structure
Synonym:

(-)-Fumagillol

Size Price Availability Quantity
5mg USD 90  USD90 In stock
10mg USD 150  USD150 In stock
25mg USD 350  USD350 In stock
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Quality Control & Documentation
Biological Activity

Fumagillol is a direct precursor of fumagillin. Fumagillin, as an antimicrobial agent, is a potent and selective inhibitor of angiogenesis.

Chemical Information
Molecular Weight 282.38
Formula C16H26O4
CAS Number 108102-51-8
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Shuang Su, et al. Fitoterapia. Three new fumagillol analogues and antifungal activity from Aspergillus fumigatus cocultured with Paraphaeosphaeria sp

[2] Janak Padia, et al. Antimicrob Agents Chemother. Discovery and Preclinical Development of Antigiardiasis Fumagillol Derivatives

[3] David A Vosburg, et al. Angew Chem Int Ed Engl. A Concise Synthesis of Fumagillol

[4] Alexander J Grenning, et al. Org Lett. Remodeling of fumagillol: discovery of an oxygen-directed oxidative Mannich reaction

[5] Bradley R Balthaser, et al. Nat Chem. Remodelling of the natural product fumagillol employing a reaction discovery approach

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Keywords: Fumagillol, (-)-Fumagillol supplier, Antibiotic, inhibitors, activators

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