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FT011

Cat. No. M14703

All AbMole products are for research use only, cannot be used for human consumption.

FT011 Structure
Synonym:

Asengeprast

Size Price Availability Quantity
1mg USD 40  USD40 In stock
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Quality Control & Documentation
Biological Activity

FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis.

FT011 (100 mg/kg b.i.d., p.o., for 4 weeks) improves the cardiac function and and myocardial remodeling in myocardial infarction rats.

Chemical Information
Molecular Weight 351.35
Formula C20H17NO5
CAS Number 1001288-58-9
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Devy Deliyanti, et al. FT011, a Novel Cardiorenal Protective Drug, Reduces Inflammation, Gliosis and Vascular Injury in Rats with Diabetic Retinopathy

[2] X Lau, et al. Attenuation of Armanni-Ebstein lesions in a rat model of diabetes by a new anti-fibrotic, anti-inflammatory agent, FT011

[3] Yuan Zhang, et al. A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction

[4] Richard E Gilbert, et al. A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat

[5] Yuan Zhang, et al. FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy

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Keywords: FT011, Asengeprast supplier, inhibitors, activators

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