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Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79 μM and 6.16 μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54 μM and 18.02 μM, respectively.
| Molecular Weight | 426.72 |
| CAS Number | 559-74-0 |
| Storage | -20°C, protect from light, dry, sealed |
[4] Thas B Alves, et al. Friedelin in Maytenus ilicifolia Is Produced by Friedelin Synthase Isoforms
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