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Frentizole is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus.
Molecular Weight | 299.35 |
Formula | C15H13N3O2S |
CAS Number | 26130-02-9 |
Solubility (25°C) | DMSO 60 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] D R Kay, et al. Arthritis Rheum. Frentizole therapy of active systemic lupus erythematosus
[4] U K Sabharwal, et al. Arthritis Rheum. Frentizole therapy in systemic lupus erythematosus
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