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FR 236924

Cat. No. M6736

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FR 236924 Structure

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Quality Control & Documentation
Biological Activity

FR 236924 is a selective PKCε activator that displays > 7-fold selectivity over other PKC isozymes. Stimulates glutamate release via presynaptic α7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo. Brain penetrant.

Chemical Information
Molecular Weight 308.5
Formula C20H36O2
CAS Number 28399-31-7
Solubility (25°C) DMSO 30.85 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gompertz, et al. Agents Actions. Acid blockade by omeprazole or ICI 162846 in a chronic duodenal ulcer model.

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Keywords: FR 236924 supplier, inhibitors, activators

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