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Forsythoside I

Cat. No. M9971
Forsythoside I Structure
Size Price Availability Quantity
5mg USD 360  USD360 In stock
10mg USD 600  USD600 In stock
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Quality Control & Documentation
Biological Activity

Forsythoside I is isolated from the fruits of Forsythia suspense (Thunb.) Vahl, it has anti-inflammatory activities.

Chemical Information
Molecular Weight 624.59
Formula C29H36O15
CAS Number 1177581-50-8
Solubility (25°C) DMSO 90 mg/mL
Storage 2-8°C, protect from light, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Fu Nan Wang, et al. Molecules. New phenylethanoid glycosides from the fruits of forsythia suspense (thunb.) vahl

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