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Flupirtine maleate is a selective potassium channel opener, NMDA receptor antagonist and GABAA receptor modulator. Flupirtine maleate is a non-opioid analgesic with muscle relaxant properties. Activates KV7 potassium channels, indirectly antagonizes NMDA receptors and modulates GABAA receptors. Exhibits neuroprotective actions in a model of cerebral ischemia in mice and reduces apoptosis and necrosis induced by noxious stimuli.
| Molecular Weight | 420.4 |
| Formula | C15H17FN4O2.C4H4O4 |
| CAS Number | 75507-68-5 |
| Solubility (25°C) | DMSO ≥ 60 mg/mL |
| Storage | 2-8°C, dry, sealed |
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