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Fluconazole

Cat. No. M5650

All AbMole products are for research use only, cannot be used for human consumption.

Fluconazole Structure
Synonym:

UK 49858

Size Price Availability Quantity
100mg USD 40  USD40 In stock
500mg USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Fluconazole (UK-49858) is a triazole antifungal agent with excellent activities against a broad range of fungi, especially against Candida albicans. Fluconazole inhibits C. albicans and Candida kefyr with IC99s range from 0.20 μg/mL to 0.39 μg/mL. Fluconazole is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol, used in the prevention of superficial and systemic fungal infections.

Chemical Information
Molecular Weight 306.27
Formula C13H12F2N6O
CAS Number 86386-73-4
Solubility (25°C) DMSO 62 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] van der Elst KC, et al. Clin Infect Dis. Insufficient fluconazole exposure in pediatric cancer patients and the need for therapeutic drug monitoring in critically ill children.

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Keywords: Fluconazole, UK 49858 supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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