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Fingolimod (FTY720 free base) is a sphingosine 1-phosphate (S1P) antagonist with an IC50 of 0.033 nM in K562 and NK cells. Fingolimod also is a pak1 activator, a immunosuppressant.
Eur J Pharmacol. 2022 Sep 15;931:175185.
Anemoside B4 ameliorates experimental autoimmune encephalomyelitis in mice by modulating inflammatory responses and the gut microbiota
Fingolimod purchased from AbMole
| Molecular Weight | 307.47 |
| Formula | C19H33NO2 |
| CAS Number | 162359-55-9 |
| Form | Solid |
| Solubility (25°C) | Ethanol 7.69 mg/mL DMSO 2 mg/mL (ultrasonic and heat to 60°C) |
| Storage | -20°C, protect from light |
[1] Mauro Zaffaroni. Fingolimod in pediatric-onset multiple sclerosis
[5] P Mandal, et al. Fingolimod: therapeutic mechanisms and ocular adverse effects
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