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FGF-basic, Rat (E. coli)

Cat. No. M11496

All AbMole products are for research use only, cannot be used for human consumption.

FGF-basic, Rat (E. coli) Structure
Synonym:

Fibroblast Growth Factor-basic; FGF-2; BFGF; FGFB; HBGF-2; bFGF; Prostatropin

Size Price Availability Quantity
10ug USD 130  USD130 In stock
50ug USD 230  USD230 In stock
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Quality Control & Documentation
  • Purity: >95% , Endotoxin < 0.2 EU/μg
  • COA
  • MSDS
Biological Activity

Expression system: E. coli
Purity: SDS-PAGE > 95%
Endotoxin: protein < 0.2 EU/μg was determined by gel coagulation
Apparent molecular weight: ~16.4 kDa, reduced by SDS-PAGE.
Storage and stability: After receiving, the product remains stable at temperatures below -70°C for up to 6 months. After recombination, the product should be stable at 4°C for 1 week or -20°C for 3 months. For long-term preservation, carrier protein (e.g. 0.1% BSA) is recommended. Avoid repeated freeze-thaw cycles.

Biological Activity: Basic fibroblast growth factor (FGF-BASIC)(E. coli), also known as FGF-2, is a multipotent cytokine and one of the prototype members of the heparin-binding FGF family. Like other MEMBERS of the FGF family, alkaline FGF has a β trilobular structure. In vivo, BASIC fibroblast factor is produced by a variety of cells, including myocardial microbiota, fibroblasts, and vascular cells. BFGF regulates a variety of processes, including cell proliferation, differentiation, survival, adhesion, motility, apoptosis, limb formation, and wound healing.

Chemical Information
Solubility (25°C) Reconstitute the lyophilized powder in ddH₂O up to 100 μg/ml.
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yong Li, et al. J Cardiovasc Pharmacol. Effect of NRG-1/ErbB signaling intervention on the differentiation of bone marrow stromal cells into sinus node-like cells

[2] F Marn, et al. J Pineal Res. Immunocytochemical localization of basic fibroblast growth factor in the rat pineal gland

[3] A U Dignass, et al. Gastroenterology. Fibroblast growth factors modulate intestinal epithelial cell growth and migration

[4] H Iwata, et al. Brain Res. Localization of basic FGF-like immunoreactivity in the hypothalamo-hypophyseal neuroendocrine axis

[5] J W Moore, et al. Development. The mRNAs encoding acidic FGF, basic FGF and FGF receptor are coordinately downregulated during myogenic differentiation

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Keywords: FGF-basic, Rat (E. coli), Fibroblast Growth Factor-basic; FGF-2; BFGF; FGFB; HBGF-2; bFGF; Prostatropin supplier, Cytokines and Growth Factors, inhibitors, activators

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