Free shipping on all orders over $ 500

Fexinidazole

Cat. No. M10339

All AbMole products are for research use only, cannot be used for human consumption.

Fexinidazole Structure
Synonym:

Hoe-239

Size Price Availability Quantity
5mg USD 80 In stock
10mg USD 130 In stock
50mg USD 360 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Fexinidazole (also known as Hoe-239) is an orally active, potent antiparasitic agent. Fexinidazole shows trypanocidal activity against T. brucei subspecies and strains with IC50s of 0.7-3.3 μM (0.2-0.9 μg/ml).

Chemical Information
Molecular Weight 279.31
Formula C12H13N3O3S
CAS Number 59729-37-2
Solubility (25°C) DMSO ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Francois Chappuis. Lancet. Oral fexinidazole for human African trypanosomiasis

[2] Susan Wyllie, et al. Sci Transl Med. The anti-trypanosome drυg fexinidazole shows potential for treating visceral leishmaniasis

[3] Marcel Kaiser, et al. Antimicrob Agents Chemother. Antitrypanosomal activity of fexinidazole, a new oral nitroimidazole drυg candidate for treatment of sleeping sickness

Related Anti-infection Products
BTZ043 Racemate

BTZ043 Racemate (BTZ038, BTZ044) is a decaprenylphosphoryl-b-D-ribose 2-epimerase inhibitor.

Enoxacin

Enoxacin is a small molecule inhibitor of binding between the B2-subunit of vacuolar H+-ATPase (V-ATPase) and microfilaments.

Posaconazole

Posaconazole is a sterol C14α demethylase inhibitor with IC50 of 0.25 nM.

Pretomanid

Pretomanid (PA-824) is a novel, orally active nitroimidazole derivative with antimycobacterial activity for use in tuberculosis-related studies.

Clofazimine

Clofazimine is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action include intercalation of clofazimine with bacterial DNA and increasing levels of cellular phospholipase A2.

  Catalog
Abmole Inhibitor Catalog




Keywords: Fexinidazole, Hoe-239 supplier, Anti-infection, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.