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Ferruginol

Cat. No. M30221

All AbMole products are for research use only, cannot be used for human consumption.

Ferruginol Structure
Synonym:

(+)-Ferruginol

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Quality Control & Documentation
Biological Activity

Ferruginol ((+)-Ferruginol), a natural diterpenoid, is an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). Ferruginol inhibits the growth of thyroid cancer cells through the induction of mitochondrial apoptosis. Ferruginol has antitumor, cardioprotective, antioxidant, gastroprotective, and neuroprotective activities.

Chemical Information
Molecular Weight 286.45
Formula C20H30O
CAS Number 514-62-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Xiaohong Wang, et al. Fitoterapia. Ferruginol prevents degeneration of dopaminergic neurons by enhancing clearance of α-synuclein in neuronal cells

[2] Guoqing Luo, et al. Med Sci Monit. Retracted: Ferruginol Diterpenoid Selectively Inhibits Human Thyroid Cancer Growth by Inducing Mitochondrial Dependent Apoptosis, Endogenous Reactive Oxygen Species (ROS) Production, Mitochondrial Membrane Potential Loss and Suppression of Mitogen-Activat䲧癐Ỵ癑㧀癏羹瘸盋ܯƌܯð�瘺嶁瘶

[3] Wen-Dong Xiong, et al. Mol Med Rep. [Retracted] Ferruginol exhibits anticancer effects in OVCAR‑3 human ovary cancer cells by inducing apoptosis, inhibition of cancer cell migration and G2/M phase cell cycle arrest

[4] Shang-Tse Ho, et al. Integr Cancer Ther. Ferruginol inhibits non-small cell lung cancer growth by inducing caspase-associated apoptosis

[5] Marcelo Bispo de Jesus, et al. Biochimie. Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells

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  Catalog
Abmole Inhibitor Catalog




Keywords: Ferruginol, (+)-Ferruginol supplier, Anti-infection, inhibitors, activators

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