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Fenspiride

Cat. No. M30200

All AbMole products are for research use only, cannot be used for human consumption.

Fenspiride Structure

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Quality Control & Documentation
Biological Activity

Fenspiride, an orally active non-steroidal antiinflammatory agent, is an antagonist of H1-histamine receptor. Fenspiride inhibites phosphodiesterase 3 (PDE3), phosphodiesterase 4 (PDE4) and phosphodiesterase 5 (PDE5) activities with -log IC50 values of 3.44, 4.16 and approximately 3.8, respectively. Fenspiride can be used for the research of respiratory diseases.

Chemical Information
Molecular Weight 260.33
Formula C15H20N2O2
CAS Number 5053-06-5
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] R A Kalekin, et al. Sud Med Ekspert. [The study of fenspiride: goals and objectives for chemical and toxicological studies]

[2] Nataliya A Kuzubova, et al. J Smooth Muscle Res. Effect of fenspiride on bronchial smooth muscle of rats with chronic obstructive pulmonary disease

[3] J C Féray, et al. Biochem Pharmacol. Fenspiride and membrane transduction signals in rat alveolar macrophages

[4] C M De Castro, et al. Eur J Pharmacol. Fenspiride: an anti-inflammatory drug with potential benefits in the treatment of endotoxemia

[5] D Bee, et al. Clin Sci (Lond). Effect of fenspiride on pulmonary function in the rat and guinea pig

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Keywords: Fenspiride supplier, Histamine Receptor, inhibitors, activators

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