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Fenspiride hydrochloride

Cat. No. M2697

All AbMole products are for research use only, cannot be used for human consumption.

Fenspiride hydrochloride Structure
Size Price Availability Quantity
100mg USD 82  USD82 In stock
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Quality Control & Documentation
Biological Activity

Fenspiride hydrochloride is a bronchodilator with anti-inflammatory properties, inhibiting phosphodiesterase 4 and phosphodiesterase 3 activities with logIC50 values of 4.16 and 3.44, respectively, in human isolated bronchi.

Chemical Information
Molecular Weight 296.79
Formula C15H20N2O2.HCl
CAS Number 5053-08-7
Form Solid
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] R A Kalekin, et al. The study of fenspiride: goals and objectives for chemical and toxicological studies

[2] Agnieszka Matuszewska, et al. Long-term administration of fenspiride has no negative impact on bone mineral density and bone turnover in young growing rats

[3] Bogdan I Cioroiu, et al. New approach for determination of the degradation products of fenspiride hydrochloride found in oral liquid formulations

[4] Nataliya A Kuzubova, et al. Effect of fenspiride on bronchial smooth muscle of rats with chronic obstructive pulmonary disease

[5] B Montes, et al. Single dose pharmacokinetics of fenspiride hydrochloride: phase I clinical trial

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