Free shipping on all orders over $ 500

Felypressin

Cat. No. M11394
Felypressin Structure
Synonym:

PLV-2

Size Price Availability Quantity
5mg USD 84  USD84 In stock
10mg USD 110  USD110 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 (Vasopressin 1) agonist. Felypressin is widely used in dental surgery.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 1040.22
Formula C46H65N13O11S2
CAS Number 56-59-7
Purity >99%
Solubility DMSO ≥ 10 mg/mL
Storage under -20°C, protect from light
Related Vasopressin Receptor Products
Desmopressin Acetate

Desmopressin is a synthetic octapeptide that is an analogue of the human hormone arginine vasopressin and has antidiuretic and procoagulant effects.

D[LEU4,LYS8]-VP TFA

D[LEU4,LYS8]-VP TFA is a selective agonist of vasopressin V1b receptors, with Ki values of 0.16 nM, 0.52 nM and 1.38 nM for rat, human and mouse V1b receptors, respectively. D[LEU4,LYS8]-VP TFA showed weak antidiuretic, vasopressor and oxytocin activity in vitro.

Terlipressin acetate

Terlipressin acetate is a vasopressin analogue and a highly selective vasopressin V1 receptor agonist that reduces visceral blood flow and portal vein pressure and controls acute varicose rupture bleeding. Terlipressin acetate has anti-inflammatory and antioxidant effects and can be used to study hepatorenal syndrome and norepinephrine-resistant septic shock.

Lixivaptan

Lixivaptan (VPA-985, WAY-VPA 985) is an orally active, selective vasopressin receptor V2 antagonist with IC50 values of 1.2 nM in humans and 2.3 nM in rats.

RG7713

RG7713 (RO5028442) is a highly effective and selective brain-osmotic vasopressin 1A (V1a) receptor antagonist with Ki values of 1 nM (hV1a) and 39 nM (mV1a).

  Catalog
Abmole Inhibitor Catalog




Keywords: Felypressin, PLV-2 supplier, Vasopressin Receptor, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.