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Favezelimab

Cat. No. M25017

All AbMole products are for research use only, cannot be used for human consumption.

Favezelimab Structure
Synonym:

MK-4280

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Quality Control & Documentation
Biological Activity

Favezelimab (MK-4280) is a humanized anti-LAG-3 monoclonal antibody that blocks the interaction between LAG-3 and its ligand MHC class II. Favezelimab has the potential for colorectal cancer (CRC) research combined with the PD-L1 inhibitor Pembrolizumab .

Chemical Information
CAS Number 2231068-83-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Martin Gutierrez, et al. Nat Med. Biomarker-directed, pembrolizumab-based combination therapy in non-small cell lung cancer: phase 2 KEYNOTE-495/KeyImPaCT trial interim results

[2] E Garralda, et al. ESMO Open. A first-in-human study of the anti-LAG-3 antibody favezelimab plus pembrolizumab in previously treated, advanced microsatellite stable colorectal cancer

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Keywords: Favezelimab, MK-4280 supplier, inhibitors, activators

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