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Faldaprevir (BI 201335) is a potent, orally active and selective noncovalent inhibitor of NS3/4A protease of HCV (hepatitis C virus) genotypes 1a and 1b, with Ki values of 2.6 and 2.0 nM, respectively. Faldaprevir inhibits HCV RNA replication, with EC50 values of 6.5 and 3.1 nM, respectively. Faldaprevir has potent antiviral activity against chronic HCV infection.
| Molecular Weight | 869.82 |
| Formula | C40H49BrN6O9S |
| CAS Number | 801283-95-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] No authors listed. Protease Inhibitors (HCV)
[3] D Campagna, et al. Drugs Today (Barc). Faldaprevir for the treatment of hepatitis C
[4] Tatsuo Kanda, et al. Int J Mol Sci. Faldaprevir for the treatment of hepatitis C
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