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Exemestane, a kind of Aromatase (CYP19A1) inhibitor, more profoundly inhibited the cell proliferation of KKU-213 cells highly expressing CYP19A1, and inhibited Aromatase in human placenta and rat ovary, with IC50 of 30 nM and 40 nM, respectively.
| Molecular Weight | 296.4 |
| Formula | C20H24O2 |
| CAS Number | 107868-30-4 |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Ana Filipa Sobral, et al. Unravelling exemestane: From biology to clinical prospects
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