Certificate of Analysis

 

Product Name: Exemestane
Catalog Number: M2281
CAS Number: 107868-30-4

Physical and Chemical Properties
Formula: C20H24O2
Molecular Weight: 296.4
Solubility: DMSO 30 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Exemestane Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Exemestane, a kind of Aromatase (CYP19A1) inhibitor, more profoundly inhibited the cell proliferation of KKU-213 cells highly expressing CYP19A1, and inhibited Aromatase in human placenta and rat ovary, with IC50 of 30 nM and 40 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.