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Etifoxine hydrochloride

Cat. No. M6720

All AbMole products are for research use only, cannot be used for human consumption.

Etifoxine hydrochloride Structure
Synonym:

HOE 36-801

Size Price Availability
5mg USD 70  USD70 4-7 Days
10mg USD 100  USD100 4-7 Days
50mg USD 280  USD280 4-7 Days
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Quality Control & Documentation
Biological Activity

Etifoxine hydrochloride is a potentiator of GABAA receptor function in cultured neurons. Preferentially acts on β2 or β3 subunit-containing GABAA receptors. Exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration.

Chemical Information
Molecular Weight 337.24
Formula C17H17ClN2O.HCl
CAS Number 56776-32-0
Form Solid
Solubility (25°C) DMSO 45 mg/mL
Water 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Horiuchi, et al. J Pharmacol Exp Ther. Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas.

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Keywords: Etifoxine hydrochloride, HOE 36-801 supplier, GABA Receptor, inhibitors, activators

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