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Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis.
| Molecular Weight | 1048.25 |
| Formula | C38H73N21O10S2 |
| CAS Number | 1262780-97-1 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Hannah A Blair. Drugs. Etelcalcetide: First Global Approval
| Related Calcium-sensing Receptor Products |
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SB-423557 is an orally active calcium-sensing receptor (CaR) antagonist (IC50=520 nM), precursor of SB-423562 (IC50=73 nM). SB-423557 is well tolerated in human and increases plasma concentrations of exogenous parathyroid hormone (PTH) and stimulates bone formation. |
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