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Eptifibatide Acetate

Cat. No. M20860

All AbMole products are for research use only, cannot be used for human consumption.

Eptifibatide Acetate Structure
Synonym:

Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2

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Quality Control & Documentation
Biological Activity

Eptifibatide Acetate is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. A disulfide bridge forms between mercaptopropionyl and cysteine. Eptifibatide prevents platelet aggregation. One study shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes.

Chemical Information
Molecular Weight 831.96
Formula C35H49N11O9S2
CAS Number 148031-34-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Benazir Fatma, et al. Antiviral Res. Alphavirus capsid protease inhibitors as potential antiviral agents for Chikungunya infection

[2] Maryam Bavand Savadkouhi, et al. Iran J Pharm Res. RP-HPLC Method Development and Validation for Determination of Eptifibatide Acetate in Bulk Drug Substance and Pharmaceutical Dosage Forms

[3] Jia Liu, et al. J Chromatogr B Analyt Technol Biomed Life Sci. Determination of eptifibatide concentration in human plasma utilizing the liquid chromatography-tandem mass spectrometry method

[4] M S Sabatine, et al. Am J Med. The use of glycoprotein IIb/IIIa inhibitors in patients with coronary artery disease

[5] A M Lincoff, et al. J Am Coll Cardiol. Platelet glycoprotein IIb/IIIa receptor blockade in coronary artery disease

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Keywords: Eptifibatide Acetate, Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 supplier, inhibitors, activators

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