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Eplerenone

Cat. No. M3256

All AbMole products are for research use only, cannot be used for human consumption.

Eplerenone Structure
Synonym:

Epoxymexrenone

Size Price Availability Quantity
5mg USD 45  USD45 In stock
10mg USD 70  USD70 In stock
25mg USD 140  USD140 In stock
50mg USD 190  USD190 In stock
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Quality Control & Documentation
Biological Activity

Eplerenone (Epoxymexrenone) is a selective, competitive and oral aldosterone antagonist with an IC50 of 138 nM. Eplerenone has low affinity for progesterone, androgen, estrogen, and glucocorticoid receptors. Eplerenone may be used in studies of hypertension and heart failure following myocardial infarction.

Chemical Information
Molecular Weight 414.49
Formula C24H30O6
CAS Number 107724-20-9
Solubility (25°C) DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tina Sc Tam, et al. Eplerenone for hypertension

[2] Mitja Lainscak, et al. Safety profile of mineralocorticoid receptor antagonists: Spironolactone and eplerenone

[3] Allan Struthers, et al. A comparison of the aldosterone-blocking agents eplerenone and spironolactone

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Keywords: Eplerenone, Epoxymexrenone supplier, inhibitors, activators

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