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Eniporide hydrochloride (EMD-96785 hydrochloride) is a Na(+)/H(+) exchange (NHE) inhibitor that specifically inhibits the NHE-1 isoform. In addition, Eniporide improves cardiac performance depression associated with myocardial ischemia/reperfusion in animals, limits infarct size, and modulates cardiac performance and high-energy phosphate content in a clinically relevant porcine model of extracorporeal circulation (CPB) and cardiac arrest.
| Molecular Weight | 356.83 |
| CAS Number | 211813-86-4 |
| Solubility (25°C) | DMSO 55 mg/mL Water 4.17 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related Na+/H+ Exchanger (NHE) Products |
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| Zoniporide dihydrochloride
Zoniporide dihydrochloride (CP-597396 dihydrochloride) is a potent and selective inhibitor of highly water-soluble sodium hydrogen exchange type 1 (NHE-1). |
| Dimethylamiloride hydrochloride
Dimethylamiloride hydrochloride is a Na+/H+ exchanger NHE inhibitor with Ki values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively. |
| NHE3-IN-1
NHE3-IN-1 is an inhibitor of sodium/proton exchanger 3 (NHE-3). |
| NHE3-IN-2
NHE3-IN-2 is a Na+/H+ exchanger 3 (NHE3) inhibitor. |
| Eniporide
Eniporide (EMD 96785) is a Na(+)/H(+) exchange (NHE) inhibitor. |
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