Dimethylamiloride hydrochloride

Cat. No. M56520

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Dimethylamiloride hydrochloride is a Na+/H+ exchanger NHE inhibitor with Ki values of 0.02, 0.25, and 14 μM for NHE1, NHE2, and NHE3, respectively.

Molecular Weight	294.14
Formula	C8H13Cl2N7O
CAS Number	2235-97-4
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

Related Na+/H+ Exchanger (NHE) Products
Zoniporide dihydrochloride Zoniporide dihydrochloride (CP-597396 dihydrochloride) is a potent and selective inhibitor of highly water-soluble sodium hydrogen exchange type 1 (NHE-1).
NHE3-IN-1 NHE3-IN-1 is an inhibitor of sodium/proton exchanger 3 (NHE-3).
NHE3-IN-2 NHE3-IN-2 is a Na+/H+ exchanger 3 (NHE3) inhibitor.
Eniporide Eniporide (EMD 96785) is a Na(+)/H(+) exchange (NHE) inhibitor.
Zoniporide hydrochloride hydrate Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM).

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